Thiols in nitric oxide synthase-containing Nocardia sp. strain NRRL 5646.

نویسندگان

  • Sungwon Lee
  • Hélène Bergeron
  • Peter C K Lau
  • John P N Rosazza
چکیده

Mycothiol (MSH) [1-D-myo-inosityl-2-(N-acetyl-l-cysteinyl)amido-2-deoxy-alpha-D-glucopyranoside], isolated as the bimane derivative, was established to be the major thiol in Nocardia sp. strain NRRL 5646, a species most closely related to Nocardia brasiliensis strain DSM 43758(T). Thiol formation and detection of MSH-dependent formaldehyde dehydrogenase activity in cell extracts are relevant to the possible modulation of nitric oxide toxicity generated by strain NRRL 5646.

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عنوان ژورنال:
  • Applied and environmental microbiology

دوره 73 9  شماره 

صفحات  -

تاریخ انتشار 2007